Plant NLRs get by with a little help from their friends

Feehan, Joanna, Castel, Baptiste, Brentham, Adam R and Jones, Jonathan (2020) Plant NLRs get by with a little help from their friends. Plant Biology, 56. pp. 99-108. ISSN 1435-8603

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Abstract

Many plant NLR (nucleotide-binding, leucine-rich repeat) immune receptors require other NLRs for their function. In pairs of chromosomally adjacent sensor/helper NLRs, the sensor typically carries an integrated domain (ID) that mimics the authentic target of a pathogen effector. The RPW8-NLR clade supports the function of many diverse plant NLRs, particularly those with a TIR N-terminal domain, in concert with a family of EP-domain containing signalling partners. The NRC clade of NLRs are required for the function of many unlinked sensor NLRs in Solanaceous plants. We evaluate recent advances in paired NLR biology in the context of the structure and possible mechanisms of the first defined plant inflammasome containing ZAR1.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
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Depositing User: LivePure Connector
Date Deposited: 25 Jun 2020 00:49
Last Modified: 21 Aug 2020 00:02
URI: https://ueaeprints.uea.ac.uk/id/eprint/75762
DOI: 10.1016/j.pbi.2020.04.006

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