Opportunities to diagnose fibrotic lung diseases in routine care: A primary care cohort study

Jones, Mark G., Nibber, Anjan, Hillyar, Christopher R. T., Chisholm, Alison, Wilson, Andrew ORCID: https://orcid.org/0000-0002-5514-4867, Maher, Toby, Kaplan, Alan, Price, David, Walsh, Simon and Richeldi, Luca and Respiratory Effectiveness Group's Interstitial Lung Disease Working Group (2020) Opportunities to diagnose fibrotic lung diseases in routine care: A primary care cohort study. Respirology, 25 (12). pp. 1274-1282. ISSN 1323-7799

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Abstract

Background and objective: Temporal trends of healthcare use in the period before a diagnosis of pulmonary fibrosis are poorly understood. We investigated trends in respiratory symptoms and LR HRU in the 10 years prior to diagnosis. Methods: We analysed a primary care clinical cohort database (UK OPCRD) and assessed patients aged ≥40 years who had an electronically coded diagnosis of pulmonary fibrosis between 2005 and 2015 and a minimum 2 years of continuous medical records prior to diagnosis. Exclusion criteria consisted of electronic codes for recognized causes of pulmonary fibrosis such as CTD, sarcoidosis or EAA. Results: Data for 2223 patients were assessed. Over the 10 years prior to diagnosis of pulmonary fibrosis, there was a progressive increase in HRU across multiple LR-related domains. Five years before diagnosis, 18% of patients had multiple healthcare contacts for LR complaints; this increased to 79% in the year before diagnosis, with 38% of patients having five or more healthcare contacts. Conclusion: There are opportunities to diagnose pulmonary fibrosis at an earlier stage; research into case-finding algorithms and strategies to educate primary care physicians is required.

Item Type:	Article
Uncontrolled Keywords:	clinical epidemiology,clinical respiratory medicine,cough,pulmonary fibrosis,respiratory function tests,pulmonary and respiratory medicine ,/dk/atira/pure/subjectarea/asjc/2700/2740
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health Faculty of Medicine and Health Sciences > Research Centres > Population Health (former - to 2025) Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Related URLs:	https://www.scopus.com/pages/publication...
Depositing User:	LivePure Connector
Date Deposited:	16 Apr 2020 00:46
Last Modified:	21 Oct 2026 23:06
URI:	https://ueaeprints.uea.ac.uk/id/eprint/74766
DOI:	10.1111/resp.13836

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