The plant-pathogen haustorial interface at a glance

Bozkurt, Tolga O. and Kamoun, Sophien ORCID: (2020) The plant-pathogen haustorial interface at a glance. Journal of Cell Science, 133 (5). ISSN 0021-9533

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Many filamentous pathogens invade plant cells through specialized hyphae called haustoria. These infection structures are enveloped by a newly synthesized plant-derived membrane called the extrahaustorial membrane (EHM). This specialized membrane is the ultimate interface between the plant and pathogen, and is key to the success or failure of infection. Strikingly, the EHM is reminiscent of host-derived membrane interfaces that engulf intracellular metazoan parasites. These perimicrobial interfaces are critical sites where pathogens facilitate nutrient uptake and deploy virulence factors to disarm cellular defenses mounted by their hosts. Although the mechanisms underlying the biogenesis and functions of these host-microbe interfaces are poorly understood, recent studies have provided new insights into the cellular and molecular mechanisms involved. In this Cell Science at a Glance and the accompanying poster, we summarize these recent advances with a specific focus on the haustorial interfaces associated with filamentous plant pathogens. We highlight the progress in the field that fundamentally underpin this research topic. Furthermore, we relate our knowledge of plant-filamentous pathogen interfaces to those generated by other plant-associated organisms. Finally, we compare the similarities between host-pathogen interfaces in plants and animals, and emphasize the key questions in this research area.

Item Type: Article
Additional Information: Funding Information: We thank the Gatsby Charitable Foundation, European Research Council (ERC), and Biotechnology and Biological Sciences Research Council (BBSRC) for funding. Open access funding provided by Imperial College London. Deposited in PMC for immediate release.
Uncontrolled Keywords: biogenesis,cells,delivery,defense-related autophagy,endoplasmic-reticulum,effector translocation,extrahaustorial membrane,haustorium,host-pathogen interface,membrane,phytophthora-infestans,powdery-mildew haustoria,protein,plant-pathogen interaction,subcellular responses,trafficking
Faculty \ School: Faculty of Science > School of Biological Sciences
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Depositing User: LivePure Connector
Date Deposited: 21 Mar 2020 01:31
Last Modified: 24 Mar 2023 09:30
DOI: 10.1242/jcs.237958

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