Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

Lucas, Stephanie J., Lord, Rianne ORCID: https://orcid.org/0000-0001-9981-129X, Wilson, Rachel L., Phillips, Roger M., Sridharan, Visuvanathar and McGowan, Patrick C. (2012) Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents. Dalton Transactions, 41. pp. 13800-13802. ISSN 1477-9226

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Abstract

Several Ru-arene and Ir–Cp* complexes have been prepared incorporating (N,N), (N,O) and (O,O) coordinating bidentate ligands and have been found to be active against both HT-29 and MCF-7 cell lines. By incorporating a biologically active ligand into a metal complex the anti-cancer activity is increased.

Item Type:	Article
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemistry of Materials and Catalysis (former - to 2025) Faculty of Science > Research Groups > Chemistry of Life Processes (former - to 2025) Faculty of Science > Research Centres > Centre for Molecular and Structural Biochemistry
Depositing User:	LivePure Connector
Date Deposited:	30 Jan 2020 04:15
Last Modified:	18 Jun 2026 18:27
URI:	https://ueaeprints.uea.ac.uk/id/eprint/73864
DOI:	10.1039/C2DT32104A

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