Rapidly progressive pulmonary haemorrhage in a case of microscopic polyangiitis

Mackay, J. ORCID: https://orcid.org/0000-0001-7558-3800 (2011) Rapidly progressive pulmonary haemorrhage in a case of microscopic polyangiitis. BMJ Case Reports. ISSN 1757-790X

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A 77-year-old gentleman, a holidaymaker in the area, presented with a 2-month history of cough productive of rust-coloured sputum and exertional dyspnoea. His initial chest x-ray showed bibasal interstitial shadowing. He then deteriorated rapidly to type 1 respiratory failure with acute renal failure. A CT chest showed bilateral alveolar haemorrhage. Testing for p-anti-neutrophil cytoplasmic antibody was strongly positive, with an anti-myeloperoxidase antibody titre of 198 units/ml (normal range 0–6 units/ml). A diagnosis of microscopic polyangitis was made. Following treatment with plasma exchange, cyclophosphamide and steroids, he made a good recovery.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: LivePure Connector
Date Deposited: 28 Jan 2020 03:52
Last Modified: 22 Oct 2022 05:44
URI: https://ueaeprints.uea.ac.uk/id/eprint/73793
DOI: 10.1136/bcr.06.2011.4336

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