APPLE-Tree (Active Prevention in People at risk of dementia: Lifestyle, bEhaviour change and Technology to REducE cognitive and functional decline) programme: protocol

Cooper, Claudia, Minihane, Anne-Marie, Aguirre, Elisa, Julie A, Barber, Bass, Nick and Rapaport, Penny (2020) APPLE-Tree (Active Prevention in People at risk of dementia: Lifestyle, bEhaviour change and Technology to REducE cognitive and functional decline) programme: protocol. International Journal of Geriatric Psychiatry, 35 (8). pp. 811-819. ISSN 0885-6230

[img] PDF (Accepted_Manuscript) - Submitted Version
Restricted to Repository staff only until 13 December 2020.

Download (1MB) | Request a copy

Abstract

Background: Observational studies indicate that approximately a third of dementia cases are attributable to modifiable cardiometabolic, physical and mental health, social and lifestyle risk factors. There is evidence that intensive behaviour change interventions targeting these factors can reduce cognitive decline. Methods and analysis: We will design and test a low intensity, secondary dementia prevention programme (‘APPLE-Tree’) to slow cognitive decline in people with Subjective Cognitive Decline with or without objective cognitive impairment. We will embed our work within social science research, to understand how dementia prevention is currently delivered and structured. We will carry out systematic reviews and around 50 qualitative interviews with stakeholders, using findings to co-produce the APPLE-Tree intervention. We plan a 10-session group intervention, involving personalised goal-setting, with individual sessions for those unable or unwilling to attend groups, delivered by psychology assistants who will be trained and supervised by clinical psychologists. The co-production group (including PPI (Public and Patient Involvement), academic and clinical/third sector professional representatives) will use the Behaviour Change Wheel Theoretical Framework to develop it. We will recruit and randomly allocate 704 participants, 1:1 to the intervention: informational control group. This sample size is sufficient to detect a between-group difference at 2 years of 0.15 on the primary outcome (cognition: modified Neuropsychological Test Battery; 90% power, 5% significance, standard deviation 0.6). Dissemination We will work with Public Health England and third sector partners to produce an effective national implementation approach, so that if our intervention works, it is used.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: LivePure Connector
Date Deposited: 17 Dec 2019 03:30
Last Modified: 01 Aug 2020 23:46
URI: https://ueaeprints.uea.ac.uk/id/eprint/73382
DOI: 10.1002/gps.5249

Actions (login required)

View Item View Item