Formal synthesis of (+)-lactacystin from l-serine

Bulman Page, Philip C., Goodyear, Ross L., Chan, Yohan, Slawin, Alexandra M.Z. and Allin, Steven M. (2019) Formal synthesis of (+)-lactacystin from l-serine. RSC Advances, 9 (51). pp. 30019-30032. ISSN 2046-2069

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Abstract

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Item Type: Article
Uncontrolled Keywords: chemistry(all),chemical engineering(all) ,/dk/atira/pure/subjectarea/asjc/1600
Faculty \ School: Faculty of Science > School of Chemistry
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Depositing User: LivePure Connector
Date Deposited: 04 Oct 2019 12:30
Last Modified: 04 Nov 2020 01:01
URI: https://ueaeprints.uea.ac.uk/id/eprint/72484
DOI: 10.1039/c9ra07244f

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