Formal synthesis of (+)-lactacystin from l-serine

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Bulman Page, Philip C., Goodyear, Ross L., Chan, Yohan, Slawin, Alexandra M.Z. and Allin, Steven M. (2019) Formal synthesis of (+)-lactacystin from l-serine. RSC Advances, 9 (51). pp. 30019-30032. ISSN 2046-2069

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Abstract

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Item Type:	Article
Uncontrolled Keywords:	chemistry(all),chemical engineering(all) ,/dk/atira/pure/subjectarea/asjc/1600
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemistry of Materials and Catalysis
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	LivePure Connector
Date Deposited:	04 Oct 2019 12:30
Last Modified:	28 Mar 2025 09:33
URI:	https://ueaeprints.uea.ac.uk/id/eprint/72484
DOI:	10.1039/c9ra07244f

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