Platinum and gold catalysis: à la carte hydroamination of terminal activated allenes with azoles

Alonso, José Miguel and Munoz-Herranz, Maria Paz ORCID: https://orcid.org/0000-0001-9037-349X (2019) Platinum and gold catalysis: à la carte hydroamination of terminal activated allenes with azoles. Organic Letters, 21 (18). pp. 7639-7644. ISSN 1523-7060

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Abstract

Nucleophilic additions to allenes catalyzed by transition metals represent a powerful tool to get selective access to diverse structures with numerous applications. Reported here is a straightforward methodology to achieve selective addition of azoles to the proximal or distal carbon of activated allenes depending on the catalyst used, unravelling a gold-platinum bimetallic catalysis approach for the 1,3-double addition of azoles to activated allenes to give 1,3-bisazole derivatives, important scaf-fold in medicinal and organometallic chemistry.

Item Type:	Article
Uncontrolled Keywords:	allenes,azoles,bimetallic catalysis,gold,platinum,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1600/1605
Faculty \ School:	Faculty of Science > School of Chemistry
Depositing User:	LivePure Connector
Date Deposited:	30 Aug 2019 11:30
Last Modified:	22 Oct 2022 05:10
URI:	https://ueaeprints.uea.ac.uk/id/eprint/72065
DOI:	10.1021/acs.orglett.9b02949

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