The basic science of bone marrow aspirate concentrate in chondral injuries

Holton, James, Imam, Mohamed, Ward, Jonathan and Snow, Martyn (2016) The basic science of bone marrow aspirate concentrate in chondral injuries. Orthopedic Reviews, 8. ISSN 2035-8164

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Abstract

There has been great interest in bone marrow aspirate concentrate (BMAC) as a cost effective method in delivering mesenchymal stem cells (MSCs) to aid in the repair and regeneration of cartilage defects. Alongside MSCs, BMAC contains a range of growth factors and cytokines to support cell growth following injury. However, there is paucity of information relating to the basic science underlying BMAC and its exact biological role in supporting the growth and regeneration of chondrocytes. The focus of this review is the basic science underlying BMAC in relation to chondral damage and regeneration.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: LivePure Connector
Date Deposited: 15 Jul 2019 09:30
Last Modified: 22 Apr 2020 08:01
URI: https://ueaeprints.uea.ac.uk/id/eprint/71733
DOI: 10.4081/or.2016.6659

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