Cognitive and mood assessment in stroke research:focused review of contemporary studies

Lees, Rosalind, Fearon, Patricia, Harrison, Jennifer K, Broomfield, Niall M and Quinn, Terence J (2012) Cognitive and mood assessment in stroke research:focused review of contemporary studies. Stroke, 43 (6). pp. 1678-1680. ISSN 0039-2499

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Abstract

BACKGROUND AND PURPOSE: International guidelines recommend cognitive and mood assessments for stroke survivors; these assessments also have use in clinical trials. However, there is no consensus on the optimal assessment tool(s). We aimed to describe use of cognitive and mood measures in contemporary published stroke trials. METHODS: Two independent, blinded assessors reviewed high-impact journals representing: general medicine (n=4), gerontology/rehabilitation (n=3), neurology (n=4), psychiatry (n=4), psychology (n=4), and stroke (n=3) January 2000 to October 2011 inclusive. Journals were hand-searched for relevant, original research articles that described cognitive/mood assessments in human stroke survivors. Data were checked for relevance by an independent clinician and clinical psychologist. RESULTS: Across 8826 stroke studies, 488 (6%) included a cognitive or mood measure. Of these 488 articles, total number with cognitive assessment was 408 (83%) and mood assessment tools 247 (51%). Total number of different assessments used was 367 (cognitive, 300; mood, 67). The most commonly used cognitive measure was Folstein's Mini-Mental State Examination (n=180 articles, 37% of all articles with cognitive/mood outcomes); the most commonly used mood assessment was the Hamilton Rating Scale of Depression(n=43 [9%]). CONCLUSIONS: Cognitive and mood assessments are infrequently used in stroke research. When used, there is substantial heterogeneity and certain prevalent assessment tools may not be suited to stroke cohorts. Research and guidance on the optimal cognitive/mood assessment strategies for clinical practice and trials is required.

Item Type: Article
Uncontrolled Keywords: affect,cognition,cohort studies,humans,practice guidelines as topic,physiopathology
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: LivePure Connector
Date Deposited: 18 Jun 2019 07:30
Last Modified: 22 Apr 2020 07:56
URI: https://ueaeprints.uea.ac.uk/id/eprint/71426
DOI: 10.1161/STROKEAHA.112.653303

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