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Walden, Grace, Liao, Xin, Riley, Graham 
ORCID: https://orcid.org/0000-0001-5528-5611, Donell, Simon, Raxworthy, Michael J. and Saeed, Aram ORCID: https://orcid.org/0000-0003-2903-5875
(2019)
Synthesis and fabrication of surface-active microparticles using a membrane emulsion technique and conjugation of model protein via strain-promoted azide–alkyne click chemistry in physiological conditions.
Bioconjugate Chemistry, 30 (3).
531–535.
ISSN 1043-1802
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Abstract
The rapid surface immobilization of protein on monodispersed polyester microcarriers is reported. A model protein, functionalized with a dibenzocyclooctyne core, immobilizes on the surface of azide-terminal polycaprolactone microcarriers within 10 min compared to 12 h for other conjugation techniques, and it is conducted in physiological conditions and in the absence of coupling reagents.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | biotechnology,bioengineering,biomedical engineering,pharmacology,pharmaceutical science,organic chemistry ,/dk/atira/pure/subjectarea/asjc/1300/1305 |
| Faculty \ School: | Faculty of Science > School of Pharmacy Faculty of Science > School of Biological Sciences Faculty of Medicine and Health Sciences > Norwich Medical School |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 12 Feb 2019 16:30 |
| Last Modified: | 27 Oct 2022 00:10 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/69916 |
| DOI: | 10.1021/acs.bioconjchem.8b00868 |
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