A systematic review of therapeutic options for non-conductive olfactory dysfunction

Addison, Alfred B. and Philpott, Carl M. (2018) A systematic review of therapeutic options for non-conductive olfactory dysfunction. Otorhinolaryngologist, 11 (2). pp. 61-71. ISSN 1752-9360

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Abstract

Background: Olfactory dysfunction affects a significant proportion of the population but appears to be more common in the elderly population (>20% of adults over 60 years old). Unfortunately, many sufferers face an apparent lack of therapeutic options when consulting with medical professionals. Method: We searched various electronic medical databases for the treatment of non-conductive olfactory dysfunction. After careful review of the abstracts and the full articles, we included publications that fulfilled our inclusion criteria and analysed the results. Results: A total of 38 publications were included in our review including 6 randomised control trials, 14 cohort studies and 18 observational studies. Conclusion: Olfactory training appears to improve non-conductive olfactory dysfunction irrespective of the aetiology. Steroids appear to have some benefit, but this may be aetiology dependent and Vitamin A and sodium citrate have shown some promise. High quality randomised control trials are still required to determine their place in managing this patient population.

Item Type: Article
Uncontrolled Keywords: anosmia,hyposmia,non-conductive,olfaction,therapy,surgery,otorhinolaryngology ,/dk/atira/pure/subjectarea/asjc/2700/2746
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 21 Jan 2019 15:30
Last Modified: 09 Nov 2020 00:55
URI: https://ueaeprints.uea.ac.uk/id/eprint/69637
DOI:

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