Compassionate use of cefiderocol as adjunctive treatment of native aortic valve endocarditis due to XDR-Pseudomonas aeruginosa

Edgeworth, Jonathan D, Merante, Domenico, Patel, Sanjay, Young, Christopher, Jones, Paul, Vithlani, Seema, Wyncoll, Duncan, Roberts, Peter, Jones, Andrew, Nagata, Tsutae Den, Ariyasu, Mari, Livermore, David M and Beale, Richard (2019) Compassionate use of cefiderocol as adjunctive treatment of native aortic valve endocarditis due to XDR-Pseudomonas aeruginosa. Clinical Infectious Diseases, 68 (11). 1932–1934. ISSN 1058-4838

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Abstract

Serious infections such as endocarditis due to extremely drug-resistance gram-negative bacteria are an increasing challenge. Here, we present successful adjunctive use of cefiderocol for a patient with persistently bacteremic healthcare-associated native aortic valve endocarditis due to an extended-spectrum beta-lactamase-positive Pseudomonas aeruginosa susceptible in vitro only to colistin, following failure of conventional therapeutic options.

Item Type: Article
Uncontrolled Keywords: cefiderocol,pseudomonas aeruginosa,drug resistance,endocarditis,microbial,microbiology (medical),infectious diseases ,/dk/atira/pure/subjectarea/asjc/2700/2726
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 05 Nov 2018 11:30
Last Modified: 19 May 2020 00:05
URI: https://ueaeprints.uea.ac.uk/id/eprint/68764
DOI: 10.1093/cid/ciy963

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