Heterobimetallic Catalysis: Platinum‐Gold‐Catalyzed Tandem Cyclization/C−X Coupling Reaction of (Hetero)Arylallenes with Nucleophiles

Alonso, José Miguel and Muñoz, Maria Paz (2018) Heterobimetallic Catalysis: Platinum‐Gold‐Catalyzed Tandem Cyclization/C−X Coupling Reaction of (Hetero)Arylallenes with Nucleophiles. Angewandte Chemie International Edition, 57 (17). pp. 4742-4746. ISSN 1433-7851

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Abstract

Heterobimetallic catalysis offers new opportunities for reactivity and selectivity but still presents challenges, and only a few metal combinations have been explored so far. Reported here is a Pt‐Au heterobimetallic catalyst system for the synthesis of a family of multi‐heteroaromatic structures through tandem cyclization/C−X coupling reaction. Au‐catalyzed 6‐endo‐cyclization takes place as the first fast step. Pt‐Au clusters are proposed to be responsible for the increased reactivity in the second step, that is, the intermolecular nucleophilic addition which occurs through an outer‐sphere mechanism by hybrid homogeneous‐heterogeneous catalysis.

Item Type: Article
Uncontrolled Keywords: heterobimetallic catalysis ,hybrid-homogeneous heterogeneous catalysis,platinum,gold,allenes
Faculty \ School: Faculty of Science > School of Chemistry
Depositing User: Pure Connector
Date Deposited: 01 Mar 2018 12:30
Last Modified: 18 Mar 2020 01:03
URI: https://ueaeprints.uea.ac.uk/id/eprint/66408
DOI: 10.1002/anie.201800670

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