Management of septated malignant pleural effusions

Banka, Radhika, Terrington, Dayle and Mishra, Eleanor K. ORCID: (2018) Management of septated malignant pleural effusions. Current Pulmonology Reports, 7 (1). pp. 1-5. ISSN 2199-2428

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Purpose of Review: We review recent studies of patients with septated malignant pleural effusions, to understand what the clinical implications for patients are and what evidence-based methods should be used to manage these effusions. Recent Findings: Fibrinolytics improve effusion size assessed radiologically in patients with a chest drain inserted for septated malignant pleural effusions but this does not translate into an improvement in breathlessness relief or pleurodesis success. Fibrinolytics have also been used in patients with septated effusions associated with indwelling pleural catheters, but dyspnoea relief has not been assessed in this population. Patients with septated effusions or extensive adhesions appear to have a worse prognosis. Summary: Patients with septated malignant pleural effusions have a poor prognosis and do not gain clinical benefit from fibrinolytics via chest drain. The role of fibrinolytics for septated effusions associated with indwelling pleural catheters requires further study.

Item Type: Article
Uncontrolled Keywords: pleural effusion,septation,fibrinolytic cancer,sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group
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Depositing User: Pure Connector
Date Deposited: 29 Jan 2018 15:30
Last Modified: 24 May 2023 03:08
DOI: 10.1007/s13665-018-0194-3


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