How sweet are our gut beneficial bacteria? A focus on protein glycosylation in Lactobacillus

Latousakis, Dimitrios and Juge, Nathalie (2018) How sweet are our gut beneficial bacteria? A focus on protein glycosylation in Lactobacillus. International Journal of Molecular Sciences, 19 (1). ISSN 1661-6596

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Protein glycosylation is emerging as an important feature in bacteria. Protein glycosylation systems have been reported and studied in many pathogenic bacteria, revealing an important diversity of glycan structures and pathways within and between bacterial species. These systems play key roles in virulence and pathogenicity. More recently, a large number of bacterial proteins have been found to be glycosylated in gut commensal bacteria. We present an overview of bacterial protein glycosylation systems (O- and N-glycosylation) in bacteria, with a focus on glycoproteins from gut commensal bacteria, particularly Lactobacilli. These emerging studies underscore the importance of bacterial protein glycosylation in the interaction of the gut microbiota with the host.

Item Type: Article
Uncontrolled Keywords: protein glycosylation,gut commensal bacteria,lactobacillus,glycoproteins,adhesins,lectins,o-glycosylation,n-glycosylation,probiotics
Faculty \ School: Faculty of Science > School of Biological Sciences
Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: Pure Connector
Date Deposited: 15 Jan 2018 16:30
Last Modified: 22 Oct 2022 03:29
DOI: 10.3390/ijms19010136


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