Apathy dimensions in Parkinson's disease

Radakovic, Ratko, Davenport, Richard, Starr, John M and Abrahams, Sharon (2018) Apathy dimensions in Parkinson's disease. International Journal of Geriatric Psychiatry, 33 (1). pp. 151-158. ISSN 0885-6230

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Abstract

OBJECTIVE: Apathy is a prominent and disabling symptom in Parkinson's disease (PD) and is a multidimensional behaviour, but which dimensions are specifically affected is unclear. Therefore, the aim of this preliminary study was to determine the psychometric properties of the Dimensional Apathy Scale (DAS) and explore the multidimensional profile of apathy in PD patients.  METHODS: Thirty-four PD patients, with 30 of their informants/carers, and 34 healthy controls, with 30 of their informants, completed the DAS, Apathy Evaluation Scale and the Geriatric Depression Scale Short Form. Motor staging and independent living status were recorded.  RESULTS: Comparative group analyses revealed that PD patients were significantly more apathetic on self-rated executive (p = 0.01) and initiation (p = 0.03) dimensions than controls, where only executive apathy was significantly higher in ratings of patients' informants/carers compared with controls' informants (p = 0.02). A third of patients were impaired on at least one apathy dimension. Additionally, patients with apathy tended to have more impaired activities of daily living, while none of the apathy dimensions related to motor disability.  CONCLUSION: Our findings show the DAS is a valid and reliable multidimensional apathy tool for use in PD. PD is characterised by an executive apathy profile as determined by informants/carers, although patients described both executive and initiation apathy. This indicates a lack of motivation for planning, organisation and attention and lack of initiation of thoughts or behaviours. Further research is needed to determine the cognitive underpinnings of this emerging apathy profile and the clinical impact in PD. Copyright © 2017 John Wiley & Sons, Ltd.

Item Type: Article
Additional Information: Copyright © 2017 John Wiley & Sons, Ltd.
Uncontrolled Keywords: apathy,parkinson's disease,motor symptoms,non-motor symptoms,depression,activities of daily living
Faculty \ School: Faculty of Medicine and Health Sciences > School of Health Sciences
Depositing User: Pure Connector
Date Deposited: 08 Jan 2018 10:57
Last Modified: 22 Jul 2020 01:55
URI: https://ueaeprints.uea.ac.uk/id/eprint/65876
DOI: 10.1002/gps.4697

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