Differential diagnosis of left ventricular hypertrophy:usefulness of multimodality imaging and tissue characterization with cardiac magnetic resonance

Izgi, Cemil, Vassiliou, Vassilios, Baksi, A John and Prasad, Sanjay K (2016) Differential diagnosis of left ventricular hypertrophy:usefulness of multimodality imaging and tissue characterization with cardiac magnetic resonance. Echocardiography, 33 (11). pp. 1765-1768. ISSN 0742-2822

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Abstract

Differential diagnosis of asymmetrical left ventricular hypertrophy may be challenging, particularly in patients with history of hypertension. A middle-aged man underwent an echocardiographic examination during workup for hypertension, which unexpectedly showed significant asymmetrical septal hypertrophy and raised suspicion for hypertrophic cardiomyopathy. Cardiovascular magnetic resonance confirmed the asymmetrical hypertrophy. No myocardial late gadolinium contrast enhancement was seen. However, precontrast T1 mapping revealed a low native myocardial T1 value. This was highly suggestive of Anderson-Fabry disease, which was subsequently proved with very low alpha galactosidase enzyme levels and mutation analysis. The case illustrates clinical usefulness of multimodality imaging and the novel tissue characterization techniques for assessment of left ventricular hypertrophy.

Item Type: Article
Additional Information: © 2016, Wiley Periodicals, Inc.
Uncontrolled Keywords: anderson-fabry disease,cardiac magnetic resonance imaging,echocardiography,hypertrophic cardiomyopathy,left ventricular hypertrophy
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: Pure Connector
Date Deposited: 10 Aug 2017 05:05
Last Modified: 22 Apr 2020 04:53
URI: https://ueaeprints.uea.ac.uk/id/eprint/64441
DOI: 10.1111/echo.13367

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