Position paper on olfactory dysfunction

Hummel, T., Whitcroft, K. L., Andrews, P., Altundag, A., Cinghi, C., Costanzo, R. M., Damm, M., Frasnelli, J., Gudziol, H., Gupta, N., Haehner, A., Holbrook, E., Hong, S. C., Hornung, D., Hüttenbrink, K. B., Kamel, R., Kobayashi, M., Konstantinidis, I., Landis, B. N., Leopold, D. A., Macchi, A., Miwa, T., Moesges, R., Mullol, J., Mueller, C. A., Ottaviano, G., Passali, G. C., Philpott, C. ORCID: https://orcid.org/0000-0002-1125-3236, Pinto, J. M., Ramakrishnan, V. J., Rombaux, P., Roth, Y., Schlosser, R. A., Shu, B., Soler, G., Stjärne, P., Stuck, B. A., Vodicka, J. and Welge-Luessen, A. (2017) Position paper on olfactory dysfunction. Rhinology. Supplement, 54 (26). ISSN 1013-0047

[thumbnail of Accepted manuscript]
PDF (Accepted manuscript) - Accepted Version
Download (932kB) | Preview


Background: Olfactory dysfunction is an increasingly recognised condition, associated with reduced quality of life and major health outcomes such as neurodegeneration and death. However, translational research in this field is limited by heterogeneity in methodological approach, including definitions of impairment, improvement and appropriate assessment techniques. Accordingly, effective treatments are limited. In an effort to encourage high quality and comparable work in this field, among others, we propose the following ideas and recommendations. Whilst full recommendations are outlined in the main document, key points include: -Patients with suspected olfactory loss should undergo a full examination of the head and neck, including rigid nasal endoscopy. -Subjective olfactory assessment should not be undertaken in isolation, given its poor reliability. -Psychophysical assessment tools used in clinical and research settings should include reliable and validated tests of odour threshold, and/or one of odour identification or discrimination. -Comprehensive chemosensory assessment should include gustatory screening. -Smell training can be helpful in patients with olfactory loss of several aetiologies. Conclusions: We hope the current manuscript will encourage clinicians and researchers to adopt a common language, and in so doing, increase the methodological quality, consistency and generalisability of work in this field.

Item Type: Article
Uncontrolled Keywords: humans,neuropsychological tests,olfaction disorders,olfactometry,olfactory perception,quality of life,journal article,review,otorhinolaryngology ,/dk/atira/pure/subjectarea/asjc/2700/2733
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit
Related URLs:
Depositing User: Pure Connector
Date Deposited: 31 Jan 2017 02:17
Last Modified: 15 Apr 2024 10:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/62231
DOI: 10.4193/Rhino16.248


Downloads per month over past year

Actions (login required)

View Item View Item