Detecting Analytes

Mount, Andy, Khondoker, Mizanur, Ciani, Ilenia, Bachmann, Till and Ghazal, Peter (2011) Detecting Analytes. UNSPECIFIED.

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The application is directed to the impedimetric determination of analyte binding, eg. DNA hybridisation using electrochemical impedance spectrometry (EIS). In one embodiment, simultaneous multi-frequency excitation is used, followed by FFT. In another, a differential method is used to monitor the rate of change of EIS variables, especially the electron transfer resistance, Ret. Combining EIS with labels allows the multiplex determination of a plurality of analytes. Also, kinetic monitoring of enzyme activity, especially of protease in wound healing, becomes possible.

Item Type: Other
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: Pure Connector
Date Deposited: 24 Sep 2016 01:08
Last Modified: 09 Jul 2021 23:43

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