Fish oil supplements, longevity and aging

Pedro de Magalhães, João, Muller, Michael ORCID: https://orcid.org/0000-0002-5930-9905, Rainger, G. Ed and Steegenga, Wilma (2016) Fish oil supplements, longevity and aging. Aging, 8 (8). pp. 1578-1582. ISSN 1945-4589

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Abstract

Fish oil supplementation is of great medical and public interest with epidemiological evidence of health benefits in humans, in particular by conferring protection against heart diseases. Its anti-inflammatory properties have also been reported. Initial results from short-lived mouse strains showed that fish oil can increase lifespan, affecting pathways like inflammation and oxidation thought to be involved in the regulation of aging. Could fish oil and its omega-3 fatty acids act as geroprotectors? Probably not. A new study by Strong et al. challenges the role for fish oil supplementation in aging. Using a large cohort of genetically heterogeneous mice in three sites, part of the Interventions Testing Program of the NIA, Strong et al. show that fish oil supplementation at either low or high dosages has no effect on the lifespan of male or female mice. Although it is still possible that fish oil supplementation has health benefits for specific age-related diseases, it does not appear to slow aging or have longevity benefits.

Item Type: Article
Additional Information: AGING applies the Creative Commons Attribution License (CCAL) to all works we publish (read the human-readable summary or the full license legal code). Under the CCAL, authors retain ownership of the copyright for their article, but authors allow anyone to download, reuse, reprint, modify, distribute, and/or copy articles in Aging journal, so long as the original authors and source are cited.
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Depositing User: Pure Connector
Date Deposited: 24 Sep 2016 00:18
Last Modified: 22 Oct 2022 01:25
URI: https://ueaeprints.uea.ac.uk/id/eprint/59969
DOI: 10.18632/aging.101021

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