The People with Asperger syndrome and anxiety disorders (PAsSA) trial: a pilot multicentre, single-blind randomised trial of group cognitive–behavioural therapy

Langdon, Peter ORCID: https://orcid.org/0000-0002-7745-1825, Murphy, Glynis, Shepstone, Lee, Wilson, Edward, Fowler, David, Heavens, David, Malovic, Aida, Russell, Alexandra, Rose, Alice and Mullineaux, Louise (2016) The People with Asperger syndrome and anxiety disorders (PAsSA) trial: a pilot multicentre, single-blind randomised trial of group cognitive–behavioural therapy. BJPsych Open, 2 (2). 179 - 186.

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Abstract

Background: There is a growing interest in using cognitive–behavioural therapy (CBT) with people who have Asperger syndrome and comorbid mental health problems. Aims: To examine whether modified group CBT for clinically significant anxiety in an Asperger syndrome population is feasible and likely to be efficacious. Method: Using a randomised assessor-blind trial, 52 individuals with Asperger syndrome were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to treatment were followed up for 24 weeks. Results: The conversion rate for this trial was high (1.6:1), while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared with those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety. Conclusions: Trials of psychological therapies with this population are feasible. Larger definitive trials are now needed.

Item Type:	Article
Additional Information:	© 2016 The Royal College of Psychiatrists This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY) licence (http://creativecommons.org/licenses/by/4.0/).
Uncontrolled Keywords:	sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User:	Pure Connector
Date Deposited:	24 Sep 2016 00:10
Last Modified:	22 Oct 2022 01:22
URI:	https://ueaeprints.uea.ac.uk/id/eprint/59891
DOI:	10.1192/bjpo.bp.115.002527

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