High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia

Alsultan, A A, Evans, B A, Elsayed, E A, Al-Thawadi, S I, Al-Taher, A Y, Amyes, S G B, Al-Dughaym, A M and Hamouda, A (2013) High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia. Journal of Medical Microbiology, 62. pp. 885-888. ISSN 0022-2615

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Abstract

Carbapenem-resistant Acinetobacter baumannii is becoming increasingly prevalent in patients with diabetes mellitus in the Middle East. We examined the relationship of these bacteria and their resistance mechanisms to the diabetic disease status of patients in Saudi Arabia. Susceptibilities of 271 isolates to carbapenems, tigecycline and colistin were determined, followed by detection of carbapenemase genes. A blaVIM gene was detected in ~95 % of isolates; blaOXA-23 and blaOXA-40 genes were also prevalent. Diabetic patients were significantly more likely to carry carbapenem-resistant isolates. Carbapenem-resistant A. baumannii is a serious problem in diabetic patients, and molecular detection of resistance mechanisms in these isolates is required.

Item Type: Article
Uncontrolled Keywords: acinetobacter infections,acinetobacter baumannii,anti-bacterial agents,bacterial proteins,carbapenems,diabetes complications,diabetes mellitus,drug resistance, bacterial,humans,microbial sensitivity tests,prevalence,saudi arabia,beta-lactamases
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 24 Sep 2016 00:09
Last Modified: 16 Jul 2020 23:36
URI: https://ueaeprints.uea.ac.uk/id/eprint/59862
DOI: 10.1099/jmm.0.057216-0

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