Random blood glucose measurement at antenatal booking to screen for overt diabetes in pregnancy:a retrospective study

Church, David, Halsall, David, Meek, Claire, Parker, Richard A, Murphy, Helen R and Simmons, David (2011) Random blood glucose measurement at antenatal booking to screen for overt diabetes in pregnancy:a retrospective study. Diabetes Care, 34 (10). pp. 2217-2219. ISSN 0149-5992

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Abstract

OBJECTIVE: To assess random venous blood glucose (RBG) measurement at antenatal booking to detect "overt diabetes in pregnancy" (ODIP). RESEARCH DESIGN AND METHODS: A retrospective analysis of regional hospital obstetric data from 2004-2008 was performed. Universal RBG screening was included at booking. Oral glucose tolerance test (OGTT) was administered if RBG >7.0 mmol/L or other indications, e.g., if a 50-g glucose challenge test was >7.7 mmol/L at 26-28 weeks. ODIP was based upon World Health Organization plasma glucose criteria for diabetes. RESULTS: RBG data were collected from 17,852/26,369 (67.7%) pregnancies around the initial antenatal visit; 3,007 women had an OGTT. The receiver operator curve area under the curve for RBG to detect ODIP was 0.86 (0.80-0.92) (assuming women without an OGTT did not have ODIP). CONCLUSIONS: RBG at booking may provide a sufficiently sensitive screening tool for the detection of ODIP. We recommend further studies and comparison with fasting glucose and HbA(1c).

Item Type: Article
Uncontrolled Keywords: adolescent,adult,blood glucose,diabetes mellitus,female,glucose tolerance test,humans,middle aged,pregnancy,retrospective studies,young adult
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Social Sciences > School of Education and Lifelong Learning
Depositing User: Pure Connector
Date Deposited: 25 May 2016 16:01
Last Modified: 22 Apr 2020 01:26
URI: https://ueaeprints.uea.ac.uk/id/eprint/59065
DOI: 10.2337/dc11-0533

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