Postmortem demonstration of intrapulmonary arteriovenous shunting

Wilkinson, M J and Fagan, D G (1990) Postmortem demonstration of intrapulmonary arteriovenous shunting. Archives of Disease in Childhood, 65 (4). pp. 435-7. ISSN 0003-9888

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The measurement of the pressure required to drive a 2% solution of gelatin across the pulmonary vascular bed of a group of 49 infants dying suddenly at less than 44 weeks' postnatal age, has shown the presence of low pressure arteriovenous shunting in 30 cases (61%). Injection of polymethylmethacrylate beads in three cases has demonstrated that the vessels that form the shunts are up to 60 microns in diameter. The presence of vessels allowing shunting at pressures as low as 0.1 kPa (1 cm H2O) could severely compromise the gas exchange function of the lung.

Item Type: Article
Uncontrolled Keywords: arteriovenous malformations,autopsy,humans,infant,infant, newborn,lung,pressure,pulmonary artery,pulmonary gas exchange,pulmonary veins
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 23 Mar 2016 12:00
Last Modified: 22 Oct 2022 00:57
DOI: 10.1136/adc.65.4.435

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