Enzymatic breakage of dimethylsulfoniopropionate - a signature molecule for life at sea

Johnston, Andrew, Green, Robert and Todd, Jonathan (2016) Enzymatic breakage of dimethylsulfoniopropionate - a signature molecule for life at sea. Current Opinion in Chemical Biology, 31. pp. 58-65. ISSN 1367-5931

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Largely using gene-based evidence, the last few years have seen real insights on the diverse ways in which different microbes break down dimethylsulfoniopropionate, an abundant anti-stress molecule that is made by marine algae, some corals and a few angiosperms. Here, we review more recent advances in which in vitro biochemical tools – including structural determinations – have shed new light on how the corresponding enzymes act on DMSP. These have revealed how enzymes in very different polypeptide families can act on this substrate, often by novel ways, and with broader implications that extend from enzymatic mechanisms to microbial ecology.

Item Type: Article
Uncontrolled Keywords: dmsp ,dms,microbial dmsp catabolism,sdg 14 - life below water ,/dk/atira/pure/sustainabledevelopmentgoals/life_below_water
Faculty \ School: Faculty of Science > School of Biological Sciences
Faculty of Science
Faculty of Science > School of Chemistry
UEA Research Groups: Faculty of Science > Research Groups > Molecular Microbiology
Depositing User: Pure Connector
Date Deposited: 12 Feb 2016 09:20
Last Modified: 22 Oct 2022 00:45
URI: https://ueaeprints.uea.ac.uk/id/eprint/57057
DOI: 10.1016/j.cbpa.2016.01.011


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