Tools
ToolsHsieh, H., McGrory, S., Leslie, F., Dawson, K., Ahmed, S., Butler, C. R., Rowe, J. B., Mioshi, E. and Hodges, J. R. (2015) The Mini-Addenbrooke's Cognitive Examination: A new assessment tool for dementia. Dementia and Geriatric Cognitive Disorders, 39 (1-2). ISSN 1420-8008
Preview |
PDF (The Mini-Addenbrooke’s Cognitive Examination)
- Published Version
Download (1MB) | Preview |
Abstract
BACKGROUND/AIMS: We developed and validated the Mini-Addenbrooke's Cognitive Examination (M-ACE) in dementia patients. Comparisons were also made with the Mini Mental State Examination (MMSE). METHOD: The M-ACE was developed using Mokken scaling analysis in 117 dementia patients [behavioural variant frontotemporal dementia (bvFTD), n = 25; primary progressive aphasia (PPA), n = 49; Alzheimer's disease (AD), n = 34; corticobasal syndrome (CBS), n = 9] and validated in an independent sample of 164 dementia patients (bvFTD, n = 23; PPA, n = 82; AD, n = 38; CBS, n = 21) and 78 controls, who also completed the MMSE. RESULTS: The M-ACE consists of 5 items with a maximum score of 30. Two cut-offs were identified: (1) ≤25/30 has both high sensitivity and specificity, and (2) ≤21/30 is almost certainly a score to have come from a dementia patient regardless of the clinical setting. The M-ACE is more sensitive than the MMSE and is less likely to have ceiling effects. CONCLUSION: The M-ACE is a brief and sensitive cognitive screening tool for dementia. Two cut-offs (25 or 21) are recommended.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cognitive screening test,frontotemporal dementia,alzheimer’s disease ,corticobasal degeneration |
| Faculty \ School: | Faculty of Medicine and Health Sciences > School of Health Sciences |
| Related URLs: | |
| Depositing User: | Pure Connector |
| Date Deposited: | 19 Jan 2016 10:00 |
| Last Modified: | 22 Oct 2022 00:41 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/56646 |
| DOI: | 10.1159/000366040 |
Actions (login required)
 |
View Item |