Memory and orientation in the logopenic and nonfluent subtypes of primary progressive aphasia

Flanagan, Emma C., Tu, Sicong, Ahmed, Samrah, Hodges, John R. and Hornberger, Michael ORCID: https://orcid.org/0000-0002-2214-3788 (2014) Memory and orientation in the logopenic and nonfluent subtypes of primary progressive aphasia. Journal of Alzheimer's Disease, 40 (1). pp. 33-36. ISSN 1387-2877

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Abstract

Memory and orientation were investigated as predictors of underlying Alzheimer's disease (AD) pathology in patients with logopenic (lv) and non-fluent (na) variants of primary progressive aphasia (PPA). Memory and orientation scores from Addenbrooke's Cognitive Examination were compared between 26 lv-PPA, 29 na-PPA, 59 AD, and 90 controls using analysis of variance. Forty-five patients underwent Pittsburgh compound B (PiB) positron emission tomography scans. Patients with lv-PPA performed poorer on memory and orientation than na-PPA and did not differ from the AD group. Post-hoc analysis on the PiB-scanned subgroup corroborated these results. Memory and orientation profiles may supplement language assessment in identifying patients with AD pathology.

Item Type: Article
Uncontrolled Keywords: lv-ppa,memory,na-ppa,orientation,pib,ppa
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: Pure Connector
Date Deposited: 04 Jan 2016 12:02
Last Modified: 23 Sep 2022 02:24
URI: https://ueaeprints.uea.ac.uk/id/eprint/55933
DOI: 10.3233/JAD-131448

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