MR perfusion imaging in human brain using the UNFAIR technique. Un-inverted flow-sensitive alternating inversion recovery

Tanabe, Jody L., Yongbi, Martin, Branch, Craig, Hrabe, Jan, Johnson, Glyn and Helpern, Joseph A. (1999) MR perfusion imaging in human brain using the UNFAIR technique. Un-inverted flow-sensitive alternating inversion recovery. Journal of Magnetic Resonance Imaging, 9 (6). pp. 761-767. ISSN 1053-1807

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Abstract

Pulsed arterial spin labeling magnetic resonance techniques have been developed recently to estimate cerebral blood flow (CBF). Flow-sensitive alternating inversion recovery (FAIR) is one such technique that has been implemented successfully in humans. Un-inverted FAIR (UNFAIR) is an alternative technique in which the flow-sensitive image is acquired following inversion of all spins outside the slice of interest, and the control image is acquired without any spin labeling. This approach is potentially more efficient than FAIR since the UNFAIR control image is entirely flow independent and need only be acquired once. Here, we describe implementation of the sequence on a clinical 1.5 T magnetic resonance system. Both FAIR and UNFAIR perfusion-weighted images were obtained from six normal volunteers. Wash-in/wash-out curves measured in cortical gray and white matter were practically identical for the two techniques, as predicted by our model.

Item Type: Article
Uncontrolled Keywords: perfusion,unfair,fair,transit times,cerebral blood flow
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 05 Oct 2015 14:48
Last Modified: 22 Apr 2020 00:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/54538
DOI: 10.1002/(SICI)1522-2586(199906)9:6<761::AID-JMRI2>3.0.CO;2-C

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