Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD

Nasef, Noha Ahmed, Mehta, Sunali, Powell, Penny, Marlow, Gareth, Wileman, Tom and Ferguson, Lynnette R (2015) Extracts of Feijoa Inhibit Toll-Like Receptor 2 Signaling and Activate Autophagy Implicating a Role in Dietary Control of IBD. PLoS One, 10 (6). ISSN 1932-6203

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Abstract

Inflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory disease affecting the gut with limited treatment success for its sufferers. This suggests the need for better understanding of the different subtypes of the disease as well as nutritional interventions to compliment current treatments. In this study we assess the ability of a hydrophilic feijoa fraction (F3) to modulate autophagy a process known to regulate inflammation, via TLR2 using IBD cell lines.

Item Type: Article
Additional Information: © 2015 Nasef et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 24 Aug 2015 09:38
Last Modified: 22 Apr 2020 00:24
URI: https://ueaeprints.uea.ac.uk/id/eprint/54142
DOI: 10.1371/journal.pone.0130910

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