Oesophageal carcinoma demonstrated by whole-body nuclear magnetic resonance imaging

Smith, F. W., Hutchison, J. M., Mallard, J. R., Johnson, G., Redpath, T. W., Selbie, R. D., Reid, A. and Smith, C. C. (1981) Oesophageal carcinoma demonstrated by whole-body nuclear magnetic resonance imaging. British Medical Journal (Clinical Research Ed.), 282. pp. 510-512. ISSN 0267-0623

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The quality of the images produced by nuclear magnetic resonance (NMR) imaging has steadily improved over the past five years. Images of the head, thorax, and abdomen have clearly shown the normal anatomy. A clinical trial of NMR imaging has therefore been started in Aberdeen to assess its diagnostic accuracy and compare it with conventional radiography and other imaging technique. The first patient examined by whole-body NMR imaging had carcinoma of the oesophagus diagnosed on barium meal examination. A technetium-99m-sulphur colloid liver scan also showed hepatic metastases. NMR imaging showed a large tumour in the lower third of the oesophagus, and areas of increased proton spin-lattice relaxation time (T1) on a section through the liver corresponded with the metastases shown on the radionuclide scan. Increased areas of T1 were present in some vertebrae, and a technetium-99m bone scan confirmed the presence of bone metastases. The NMR images in this patient compared well with the images from other techniques. The continuing clinical trial may show that NMR is an accurate diagnostic aid which will complement existing techniques for diagnosing intrathoracic and intra-abdominal conditions.

Item Type: Article
Additional Information: M1 - 6263 Smith, F W Hutchison, J M Mallard, J R Johnson, G Redpath, T W Selbie, R D Reid, A Smith, C C eng Comparative Study ENGLAND Clinical research ed. 1981/02/14 Br Med J (Clin Res Ed). 1981 Feb 14;282(6263):510-2.
Uncontrolled Keywords: adenocarcinoma,diagnosis,radiography,radionuclide imaging aged esophageal neoplasms,radionuclide imaging humans liver neoplasms,secondary magnetic resonance spectroscopy,diagnostic use male ,tomography ultrasonography
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit
Depositing User: Pure Connector
Date Deposited: 19 Aug 2015 13:20
Last Modified: 21 Oct 2022 01:09
URI: https://ueaeprints.uea.ac.uk/id/eprint/54103
DOI: 10.1136/bmj.282.6263.510

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