Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer:a nested case-control study

Gilbert, Rebecca, Bonilla, Carolina, Metcalfe, Chris, Lewis, Sarah, Evans, David M, Fraser, William D, Kemp, John P, Donovan, Jenny L, Hamdy, Freddie C, Neal, David E, Lane, J Athene, Smith, George Davey, Lathrop, Mark and Martin, Richard M (2015) Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer:a nested case-control study. Cancer Causes & Control, 26 (2). pp. 205-18. ISSN 0957-5243

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Abstract

Vitamin D pathway single nucleotide polymorphisms (SNPs) are potentially useful proxies for investigating whether circulating vitamin D metabolites [total 25-hydroxyvitamin-D, 25(OH)D; 1,25-dihydroxyvitamin, 1,25(OH)2D] are causally related to prostate cancer. We investigated associations of sixteen SNPs across seven genes with prostate-specific antigen-detected prostate cancer.

Item Type: Article
Additional Information: This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
Uncontrolled Keywords: prostate cancer,vitamin d,vitamin d pathway genes,25 hydroxyvitamin-d,1,25-dihydroxyvitamin-d
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 29 Apr 2015 10:36
Last Modified: 22 Jul 2020 00:14
URI: https://ueaeprints.uea.ac.uk/id/eprint/53202
DOI: 10.1007/s10552-014-0500-5

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