Syncope in hypertrophic cardiomyopathy:mechanisms and consequences for treatment

Williams, Lynne and Frenneaux, Michael (2007) Syncope in hypertrophic cardiomyopathy:mechanisms and consequences for treatment. EP-Europace, 9 (9). pp. 817-822. ISSN 1099-5129

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Hypertrophic cardiomyopathy (HCM) is an inherited disease with marked phenotypic variability that includes the extent of hypertrophy, the presence and severity of symptoms, and the natural history of the disease. Symptoms of impaired consciousness (syncope and pre-syncope) occur in approximately 15-25% of patients with hypertrophic cardiomyopathy (HCM). In young patients a history of recurrent syncope is associated with an increased risk of sudden death. Detailed investigations identify a probable mechanism in a minority of these, usually paroxysmal atrial fibrillation or ventricular tachycardia. In the majority, however, no likely mechanism is found despite extensive investigation. Although this may be the case, it is still of vital importance to exclude potentially treatable causes of syncope.

Item Type: Article
Uncontrolled Keywords: arrhythmias, cardiac,cardiomyopathies,cardiomyopathy, hypertrophic,death, sudden, cardiac,defibrillators, implantable,electrocardiography,humans,phenotype,risk,risk factors,syncope,tachycardia, paroxysmal,tachycardia, ventricular
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User: Pure Connector
Date Deposited: 23 Mar 2015 13:14
Last Modified: 23 Apr 2023 01:03
DOI: 10.1093/europace/eum093

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