ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults

Pironi, Loris, Arends, Jann, Baxter, Janet, Bozzetti, Federico, Burgos Peláez, Rosa, Cuerda, Cristina, Forbes, Alastair ORCID:, Gabe, Simon, Gillanders, Lyn, Holst, Mette, Jeppesen, Palle Bekker, Joly, Francisca, Kelly, Darlene, Klek, Stanislaw, Irtun, Øivind, Olde Damink, Sw, Panisic, Marina, Rasmussen, Henrik Højgaard, Staun, Michael, Szczepanek, Kinga, Van Gossum, André, Wanten, Geert, Schneider, Stéphane Michel and Shaffer, Jon (2015) ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. Clinical Nutrition, 34 (2). pp. 171-180. ISSN 0261-5614

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Background & aims: Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its “home artificial nutrition and chronic IF” and “acute IF” special interest groups to write recommendations on these issues. Methods: After a Medline Search, in December 2013, for “intestinal failure” and “review”[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings. Results: The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”. Conclusions: This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.

Item Type: Article
Additional Information: Copyright © 2014 The Authors. Licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)
Uncontrolled Keywords: intestinal failure,hpn,tpn,short bowel syndrome,chronic intestinal pseudo-obstruction,enterocutaneous fistulas,home parenteral nutrition,intestinal transplantation
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology
Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User: Pure Connector
Date Deposited: 09 Mar 2015 07:30
Last Modified: 20 Oct 2022 22:35
DOI: 10.1016/j.clnu.2014.08.017

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