Supine rest reduces platelet activation and aggregation

Broadley, Andrew J. M., Gapper, Peter, Schmitt, Matthias and Frenneaux, Michael P. (2003) Supine rest reduces platelet activation and aggregation. Platelets, 14 (1). pp. 3-7. ISSN 0953-7104

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Platelet activation and aggregation are central processes in acute coronary syndromes and myocardial infarction, and are stimulated by physical and mental stress. However, it is not known if and to what extent the "ordinary" stress inherent in a person's daily routine contributes to platelet activation and aggregation. We measured platelet activation and aggregation in 12 healthy non-smokers, before and after 45 min supine rest in a calm environment. This simple manouver resulted in a highly significant fall in platelet aggregation (7.9-4.4 ohms, p

Item Type: Article
Uncontrolled Keywords: biological markers,catecholamines,humans,p-selectin,platelet activation,platelet aggregation,rest,supine position,beta-thromboglobulin,von willebrand factor
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User: Pure Connector
Date Deposited: 09 Mar 2015 07:30
Last Modified: 11 Aug 2023 13:30
DOI: 10.1080/0953710021000034447

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