Arterial distensibility:acute changes following dynamic exercise in normal subjects

Naka, Katerina K, Tweddel, Ann C, Parthimos, Dimitris, Henderson, Andrew, Goodfellow, Jonathan and Frenneaux, Michael P (2003) Arterial distensibility:acute changes following dynamic exercise in normal subjects. American Journal of Physiology - Heart and Circulatory Physiology, 284 (3). H970-8. ISSN 0363-6135

Full text not available from this repository.


The time course of acute changes in large artery distensibility immediately and for 60 min following maximum treadmill exercise in normal subjects was characterized by simultaneously measuring upper and lower limb pulse wave velocity (PWV). A new oscillometric technique was used, which has proven to be sensitive to changes in distensibility induced by acute changes in vascular tone independently of blood pressure. The observed changes in PWV are attributable to changes in vascular tone corresponding to recovery from a systemic net constrictor response and a local net dilator response to exercise with persisting postexercise vasodilatation. They are inadequately explained by associated changes in blood pressure and cannot be attributed to changes in heart rate or viscosity. Modeled as a system of n coupled linear differential equations, the minimum (and adequate) order required to reproduce these patterns was n = 1 for the upper and n = 2 for the exercising lower limb. The economy of the solution suggests entrainment among the multiple interactive mechanisms governing vasomotor control.

Item Type: Article
Uncontrolled Keywords: adolescent,adult,arm,arteries,blood pressure,exercise test,female,heart rate,humans,leg,male,middle aged,models, cardiovascular,physical exertion,pulsatile flow,reference values,time factors,vasodilation
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cardiovascular and Metabolic Health
Depositing User: Pure Connector
Date Deposited: 09 Mar 2015 07:30
Last Modified: 22 Apr 2023 22:31
DOI: 10.1152/ajpheart.00529.2002

Actions (login required)

View Item View Item