The effect of GH replacement therapy on endothelial function and oxidative stress in adult growth hormone deficiency

Evans, L M, Davies, J S, Anderson, R A, Ellis, G R, Jackson, S K, Lewis, M J, Frenneaux, M P, Rees, A and Scanlon, M F (2000) The effect of GH replacement therapy on endothelial function and oxidative stress in adult growth hormone deficiency. European Journal of Endocrinology, 142 (3). pp. 254-262. ISSN 0804-4643

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Abstract

Controversy persists with regard to the atherogenic risk associated with adult growth hormone deficiency (GHD). Endothelial dysfunction and enhanced oxidative stress are early features of atherogenesis. Therefore, we have studied the effect of three months of low dose GH replacement therapy (0.03IU/kg/day) on these parameters in GHD adults.

Item Type: Article
Uncontrolled Keywords: adult,blood flow velocity,blood pressure,case-control studies,endothelium, vascular,female,free radicals,growth hormone,humans,hypopituitarism,male,middle aged,oxidative stress,time factors,treatment outcome
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: Pure Connector
Date Deposited: 09 Mar 2015 07:29
Last Modified: 21 Apr 2020 23:54
URI: https://ueaeprints.uea.ac.uk/id/eprint/52426
DOI:

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