A brief synthesis of the Aplasmomycin tetrahydrofuran

Bew, S.P., Knight, D.W. and Middleton, R.J. (2000) A brief synthesis of the Aplasmomycin tetrahydrofuran. Tetrahedron Letters, 41 (22). pp. 4453-4456. ISSN 0040-4039

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Abstract

A highly stereoselective iodocyclisation of the 3-alkene-1,2-diol 9, derived from asymmetric dihydroxylation of the dienyl benzoate 8, gives the β-iodotetrahydrofuran 10 and thence the Aplasmomycin precursor 13, following deiodination and Mitsunobu inversion. (C) 2000 Elsevier Science Ltd.

Item Type: Article
Faculty \ School: Faculty of Science > School of Chemistry
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Depositing User: Pure Connector
Date Deposited: 02 Feb 2015 13:58
Last Modified: 21 Apr 2020 23:48
URI: https://ueaeprints.uea.ac.uk/id/eprint/51967
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