A brief synthesis of the Aplasmomycin tetrahydrofuran

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Bew, Sean P., Knight, David W. and Middleton, Robert J. (2000) A brief synthesis of the Aplasmomycin tetrahydrofuran. Tetrahedron Letters, 41 (22). pp. 4453-4456. ISSN 0040-4039

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Abstract

A highly stereoselective iodocyclisation of the 3-alkene-1,2-diol 9, derived from asymmetric dihydroxylation of the dienyl benzoate 8, gives the β-iodotetrahydrofuran 10 and thence the Aplasmomycin precursor 13, following deiodination and Mitsunobu inversion. (C) 2000 Elsevier Science Ltd.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Chemistry (former - to 2024)
UEA Research Groups:	Faculty of Science > Research Groups > Chemistry of Materials and Catalysis Faculty of Science > Research Groups > Synthetic Chemistry (former - to 2017)
Related URLs:	http://www.scopus.com/inward/record.url?...
Depositing User:	Pure Connector
Date Deposited:	02 Feb 2015 13:58
Last Modified:	28 Mar 2025 06:24
URI:	https://ueaeprints.uea.ac.uk/id/eprint/51967
DOI:	10.1016/S0040-4039(00)00614-6

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