Tumour genomic and microenvironmental heterogeneity as integrated predictors for prostate cancer recurrence: a retrospective study

Lalonde, Emilie, Ishkanian, Adrian S., Sykes, Jenna, Fraser, Michael, Ross-Adams, Helen, Erho, Nicholas, Dunning, Mark J., Halim, Silvia, Lamb, Alastair D., Moon, Nathalie C., Zafarana, Gaetano, Warren, Anne Y., Meng, Xianyue, Thoms, John, Grzadkowski, Michal R., Berlin, Alejandro, Have, Cherry L., Ramnarine, Varune R., Yao, Cindy Q., Malloff, Chad A., Lam, Lucia L., Xie, Honglei, Harding, Nicholas J., Mak, Denise Y. F., Chu, Kenneth C., Chong, Lauren C., Sendorek, Dorota H., P'ng, Christine, Collins, Colin C., Squire, Jeremy A., Jurisica, Igor, Cooper, Colin ORCID: https://orcid.org/0000-0003-2013-8042, Eeles, Rosalind, Pintilie, Melania, Dal Pra, Alan, Davicioni, Elai, Lam, Wan L., Milosevic, Michael, Neal, David E., van der Kwast, Theodorus, Boutros, Paul C. and Bristow, Robert G. (2014) Tumour genomic and microenvironmental heterogeneity as integrated predictors for prostate cancer recurrence: a retrospective study. The Lancet Oncology, 15 (13). 1521–1532. ISSN 1470-2045

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Abstract

Clinical prognostic groupings for localised prostate cancers are imprecise, with 30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We aimed to test combined genomic and microenvironmental indices in prostate cancer to improve risk stratification and complement clinical prognostic factors.

Item Type: Article
Additional Information: Published under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Cancer Studies
Depositing User: Pure Connector
Date Deposited: 02 Jan 2015 11:26
Last Modified: 20 Oct 2022 21:32
URI: https://ueaeprints.uea.ac.uk/id/eprint/51081
DOI: 10.1016/S1470-2045(14)71021-6

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