Tumour genomic and microenvironmental heterogeneity as integrated predictors for prostate cancer recurrence: a retrospective study

Lalonde, Emilie, Ishkanian, Adrian S, Sykes, Jenna, Fraser, Michael, Ross-Adams, Helen, Erho, Nicholas, Dunning, Mark J, Halim, Silvia, Lamb, Alastair D, Moon, Nathalie C, Zafarana, Gaetano, Warren, Anne Y, Meng, Xianyue, Thoms, John, Grzadkowski, Michal R, Berlin, Alejandro, Have, Cherry L, Ramnarine, Varune R, Yao, Cindy Q, Malloff, Chad A and Cooper, Colin (2014) Tumour genomic and microenvironmental heterogeneity as integrated predictors for prostate cancer recurrence: a retrospective study. The Lancet Oncology, 15 (13). 1521–1532. ISSN 1470-2045

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Abstract

Clinical prognostic groupings for localised prostate cancers are imprecise, with 30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We aimed to test combined genomic and microenvironmental indices in prostate cancer to improve risk stratification and complement clinical prognostic factors.

Item Type: Article
Additional Information: Published under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 02 Jan 2015 11:26
Last Modified: 31 Oct 2020 00:43
URI: https://ueaeprints.uea.ac.uk/id/eprint/51081
DOI: 10.1016/S1470-2045(14)71021-6

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