Low-grade liposarcoma with osteosarcomatous dedifferentiation:radiological and histological features

Toms, Andoni P, White, Lawrence M, Kandel, Rita and Bell, Robert S (2003) Low-grade liposarcoma with osteosarcomatous dedifferentiation:radiological and histological features. Skeletal Radiology, 32 (5). pp. 286-289. ISSN 0364-2348

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We describe the radiological and pathological findings of a rare case of a low-grade liposarcoma associated with a high-grade osteosarcomatous component in a 78-year-old woman. Pre-operative imaging demonstrated a well-encapsulated homogeneous fatty tumour in the right buttock deep to the gluteal musculature. Centrally within the fatty tumour a region of increased soft tissue attenuation on CT and heterogeneous high signal on fat-saturated T2-weighted MRI was seen with amorphous calcification/ossification. Histological assessment revealed a low-grade liposarcoma containing an area of dedifferentiation that resembled an osteosarcoma. We describe the radiological-pathological findings in this rarely reported clinical entity and discuss the differential diagnosis of calcification within lipomatous tumours.

Item Type: Article
Uncontrolled Keywords: aged,buttocks,calcinosis,female,humans,liposarcoma,muscle neoplasms,muscle, skeletal
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 15 Sep 2014 13:24
Last Modified: 21 Oct 2022 00:08
URI: https://ueaeprints.uea.ac.uk/id/eprint/50119
DOI: 10.1007/s00256-002-0614-9

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