Radiolabeled leucocyte imaging in diffuse granulomatous involvement of the meninges in Wegener's granulomatosis:scintigraphic findings and their role in monitoring treatment response to specific immunotherapy (humanized monoclonal antilymphocyte antibodies)

Murphy, Joseph M., Balan, Kottekkattu K., Toms, Andoni, Gomez-Anson, Beatriz and Lockwood, Martin (2000) Radiolabeled leucocyte imaging in diffuse granulomatous involvement of the meninges in Wegener's granulomatosis:scintigraphic findings and their role in monitoring treatment response to specific immunotherapy (humanized monoclonal antilymphocyte antibodies). American Journal of Neuroradiology, 21 (8). pp. 1460-1465. ISSN 0195-6108

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Abstract

Diffuse involvement of the meninges by remote granulomas in Wegener's granulomatosis is rare. This study reports the radiolabeled leucocyte imaging findings in five such patients. The diagnosis was made by MR imaging in five patients and confirmed in four by findings at meningeal biopsy. The potential role of serial radiolabeled leucocyte examinations in assessing treatment response is discussed.

Item Type: Article
Uncontrolled Keywords: adult,aged,antibodies, monoclonal,antilymphocyte serum,female,humans,immunotherapy,indium radioisotopes,leukocytes,magnetic resonance imaging,male,meninges,middle aged,radiopharmaceuticals,technetium tc 99m exametazime,wegener granulomatosis
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: Pure Connector
Date Deposited: 15 Sep 2014 13:16
Last Modified: 21 Apr 2020 23:25
URI: https://ueaeprints.uea.ac.uk/id/eprint/50111
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