Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure

Jeppesen, Palle B, Pertkiewicz, Marek, Messing, Bernard, Iyer, Kishore, Seidner, Douglas L, O'keefe, Stephen J D, Forbes, Alastair ORCID: https://orcid.org/0000-0001-7416-9843, Heinze, Hartmut and Joelsson, Bo (2012) Teduglutide reduces need for parenteral support among patients with short bowel syndrome with intestinal failure. Gastroenterology, 143 (6). 1473-1481.e3. ISSN 0016-5085

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Abstract

Teduglutide, a glucagon-like peptide 2 analogue, might restore intestinal structural and functional integrity by promoting growth of the mucosa and reducing gastric emptying and secretion. These factors could increase fluid and nutrient absorption in patients with short bowel syndrome with intestinal failure (SBS-IF). We performed a prospective study to determine whether teduglutide reduces parenteral support in patients with SBS-IF.

Item Type:	Article
Additional Information:	Copyright © 2012 AGA Institute. Published by Elsevier Inc. All rights reserved.
Uncontrolled Keywords:	adolescent,adult,aged,aged, 80 and over,biological markers,citrulline,dose-response relationship, drug,double-blind method,endpoint determination,female,humans,injections, subcutaneous,intestinal absorption,intestinal diseases,intestines,male,middle aged,parenteral nutrition,peptides,prospective studies,short bowel syndrome,treatment outcome,video recording,young adult
Faculty \ School:	Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups:	Faculty of Medicine and Health Sciences > Research Groups > Gastroenterology and Gut Biology Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Depositing User:	Pure Connector
Date Deposited:	06 Aug 2014 10:48
Last Modified:	20 Oct 2022 19:31
URI:	https://ueaeprints.uea.ac.uk/id/eprint/49805
DOI:	10.1053/j.gastro.2012.09.007

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