Perianal fistulae in Crohn's Disease:current and future approaches to treatment

Keshaw, Hussila, Foong, Keen S, Forbes, Alastair ORCID: and Day, Richard M (2010) Perianal fistulae in Crohn's Disease:current and future approaches to treatment. Inflammatory Bowel Diseases, 16 (5). pp. 870-80. ISSN 1078-0998

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: affecting sphincter integrity and continence. Traditional surgical and medical approaches are not without their limitations and may result in either comorbidity, such as fecal incontinence, or incomplete healing of the fistulae. Over the last 2 decades these limitations have led to a paradigm shift toward the use of biomaterials, and more recently cell-based therapies, which have met with variable degrees of success. This review discusses the traditional and current methods of treatment, as well as emerging and possible alternative approaches that may improve fistula healing.

Item Type: Article
Uncontrolled Keywords: anti-bacterial agents,crohn disease,humans,immunosuppressive agents,rectal fistula
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 10:48
Last Modified: 21 Oct 2022 00:02
DOI: 10.1002/ibd.21137

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