Associations between dietary flavonoid intakes and bone health in a Scottish population

Hardcastle, Antonia C, Aucott, Lorna, Reid, David M and Macdonald, Helen M (2011) Associations between dietary flavonoid intakes and bone health in a Scottish population. Journal of Bone and Mineral Research, 26 (5). pp. 941-7. ISSN 0884-0431

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Flavonoids are bioactive polyphenols found particularly in fruit and vegetables, but little is known about their role in bone health in humans. The aim of this observational study was to investigate whether dietary flavonoid intake was associated with bone mineral density (BMD) and bone resorption in a large group of perimenopausal Scottish women. Over 3000 women completed a food frequency questionnaire as part of an osteoporosis screening study. The diets were analyzed for flavonoid intake using a food composition database. BMD was measured at the femoral neck (FN) and lumbar spine (LS) by dual-energy X-ray absorptiometry (DXA). Free pyridinoline (PYD) and deoxypyridinoline (DPD) were measured by high-performance liquid chromatography (HPLC) in second early morning fasted urine samples. The mean flavonoid intake of the diet was 307 ±199 mg/d. The catechin family contributed the most to flavonoid intakes (55%), and the flavones the least (

Item Type: Article
Additional Information: Copyright © 2011 American Society for Bone and Mineral Research.
Uncontrolled Keywords: amino acids,bone density,bone and bones,cohort studies,creatinine,diet,feeding behavior,female,femur neck,flavonoids,health,humans,linear models,middle aged,postmenopause,questionnaires,reproducibility of results,scotland
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 10:46
Last Modified: 21 Oct 2022 00:01
DOI: 10.1002/jbmr.285

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