Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease

Stack, W A, Mann, S D, Roy, A J, Heath, P, Sopwith, M, Freeman, J, Holmes, G, Long, R, Forbes, A and Kamm, M A (1997) Randomised controlled trial of CDP571 antibody to tumour necrosis factor-alpha in Crohn's disease. The Lancet, 349 (9051). pp. 521-524. ISSN 0140-6736

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Abstract

Tumour necrosis factor-alpha (TNF alpha) is thought to have a central role in the pathogenesis of Crohn's disease. We tested the hypothesis that CDP571, a genetically engineered human antibody to TNF alpha, is effective in modifying disease activity in patients with moderately active Crohn's disease.

Item Type: Article
Uncontrolled Keywords: adolescent,adult,aged,antibodies,c-reactive protein,crohn disease,double-blind method,glycoproteins,humans,middle aged,placebos,remission induction,tumor necrosis factor-alpha
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 06 Aug 2014 10:56
Last Modified: 21 Apr 2020 23:16
URI: https://ueaeprints.uea.ac.uk/id/eprint/49550
DOI: 10.1016/S0140-6736(97)80083-9

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