A preliminary study of the bioavailability of iron- and zinc-glycine chelates

Fairweather-Tait, Susan J. ORCID: https://orcid.org/0000-0002-1413-5569, Fox, Thomas E., Wharf, S. Gabrielle and Ghani, Nawalyah A. (1992) A preliminary study of the bioavailability of iron- and zinc-glycine chelates. Food Additives and Contaminants, 9 (1). pp. 97-101. ISSN 0265-203X

Full text not available from this repository. (Request a copy)


Groups of rats were fed diets containing marginal levels of Fe and Zn as glycine chelates (tradename 'Chelazome', Albion Laboratories, Verona, New Jersey, USA), or the same level of mineral as ferrous sulphate or zinc carbonate. The Fe diets were fed to weanling rats for 4 weeks and the Zn diets to young adult rats for 5 weeks. Blood Hb concentrations were significantly higher in the group fed Fe-chelazome than ferrous sulphate, 149 and 128 g/l respectively (P less than 0.001), but PCV and liver Fe concentrations were similar between the two groups. No difference in plasma Zn, pancreas, testes or femur Zn concentrations were observed between the two Zn groups, indicating that Zn-chelazome has no advantage over zinc carbonate. The results of this preliminary study indicate that Fe-chelazome has a higher bioavailability than ferrous sulphate and merits further study.

Item Type: Article
Uncontrolled Keywords: animals,biological availability,carbonates,chelating agents,delayed-action preparations,ferrous compounds,glycine,iron chelating agents,male,random allocation,rats,rats, wistar,spectrophotometry, atomic,zinc,zinc compounds
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Chemistry
Depositing User: Pure Connector
Date Deposited: 05 Aug 2014 12:50
Last Modified: 24 Oct 2022 06:33
URI: https://ueaeprints.uea.ac.uk/id/eprint/49234
DOI: 10.1080/02652039209374049

Actions (login required)

View Item View Item