Riboflavin deficiency and iron absorption in adult Gambian men

Fairweather-Tait, S J, Powers, H J, Minski, M J, Whitehead, J and Downes, R (1992) Riboflavin deficiency and iron absorption in adult Gambian men. Annals of Nutrition & Metabolism, 36 (1). pp. 34-40. ISSN 0250-6807

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Abstract

Iron absorption from 3.38 mg 58Fe was measured in riboflavin-deficient Gambian men with haemoglobin (Hb) less than 11.5 g/dl before and after oral riboflavin therapy, and the results compared with a group not receiving riboflavin. Riboflavin status (as determined by erythrocyte glutathione reductase activation coefficient) and Hb increased in teh riboflavin-supplemented but not placebo group. Plasma ferritin levels were low and did not change in either group. There was very wide variation in percentage iron absorption between individuals and also within single individuals on two separate occasions but no measurable change with riboflavin supplementation. The results of the study indicate that the efficiency of iron utilization is impaired in riboflavin deficiency, but that iron absorption is unaffected.

Item Type: Article
Uncontrolled Keywords: administration, oral,adolescent,adult,gambia,humans,intestinal absorption,iron,male,middle aged,riboflavin,riboflavin deficiency
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: Pure Connector
Date Deposited: 05 Aug 2014 12:50
Last Modified: 21 Apr 2020 23:12
URI: https://ueaeprints.uea.ac.uk/id/eprint/49232
DOI: 10.1159/000177696

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