True fractional calcium absorption in Chinese children measured with stable isotopes (42Ca and 44Ca)

Lee, Warren T., Leung, Sophie S. F., Fairweather-Tait, Susan J. ORCID:, Leung, Dora M. Y., Tsang, Heidi S. Y., Eagles, John, Fox, Tom, Wang, S. H., Xu, Y. C., Zeng, W. P., Lau, Joseph and Maseri, J. R. L. (1994) True fractional calcium absorption in Chinese children measured with stable isotopes (42Ca and 44Ca). British Journal of Nutrition, 72 (6). pp. 883-897. ISSN 0007-1145

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True fractional Ca absorption (TFCA) was compared in children with different habitual Ca intakes using a double-label stable-isotope technique. Chinese children aged 7 years from Hongkong (n22) and Jiangmen (n12) participated in the study. An oral administration of 8 mg 44Ca in 100 g chocolate milk was given shortly after an intravenous injection of 0.75 mg 42Ca. Ca isotopic ratios were determined in urine samples collected 24 h later using thermal-ionization mass spectrometry. There was no significant difference in TFCA between Jiangmen and Hongkong children (P = 0.16). TFCA of a lower-Ca-intake group (Ca 500 mg/d, n15) with mean Ca intake 862 mg/d was 54.8 (SD 7.3)%; the difference in TFCA was significant (P = 0.016). Serum levels of 25-hydroxycholecalciferol of the children were adequate (33.7 (SD 7.7) ng/ml). The present study indicates that growing children accustomed to a low-Ca diet appear to be able to enhance their absorptive capacity. If it is assumed that dietary Ca absorption by Chinese children resembles their TFCA from a single meal of chocolate milk, then the recommended dietary allowance (RDA) for Ca for Chinese children would be lower than the US RDA (800 mg/d), which is based on an estimated 40% Ca absorption as reported for Caucasian children. A comparative absorption study is necessary to determine whether there is any difference in TFCA between Caucasian and Chinese children.

Item Type: Article
Uncontrolled Keywords: body height,body weight,calcifediol,calcium,calcium isotopes,child,china,diet,female,humans,intestinal absorption,male,mass spectrometry
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Chemistry
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine
Depositing User: Pure Connector
Date Deposited: 25 Jul 2014 12:42
Last Modified: 24 Oct 2022 06:32
DOI: 10.1079/BJN19940093

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