The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants

Kunze, Gernot, Zipfel, Cyril, Robatzek, Silke, Niehaus, Karsten, Boller, Thomas and Felix, Georg (2004) The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants. The Plant Cell, 16 (12). pp. 3496-3507. ISSN 1040-4651

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Abstract

Innate immunity is based on the recognition of pathogen-associated molecular patterns (PAMPs). Here, we show that elongation factor Tu (EF-Tu), the most abundant bacterial protein, acts as a PAMP in Arabidopsis thaliana and other Brassicaceae. EF-Tu is highly conserved in all bacteria and is known to be N-acetylated in Escherichia coli. Arabidopsis plants specifically recognize the N terminus of the protein, and an N-acetylated peptide comprising the first 18 amino acids, termed elf18, is fully active as inducer of defense responses. The shorter peptide, elf12, comprising the acetyl group and the first 12 N-terminal amino acids, is inactive as elicitor but acts as a specific antagonist for EF-Tu-related elicitors. In leaves of Arabidopsis plants, elf18 induces an oxidative burst and biosynthesis of ethylene, and it triggers resistance to subsequent infection with pathogenic bacteria.

Item Type: Article
Uncontrolled Keywords: acetylation,amino acid sequence,arabidopsis,bacterial proteins,escherichia coli,ethylenes,flagellin,immunity, innate,models, molecular,molecular sequence data,peptide elongation factor tu,peptide fragments,plant diseases,plant leaves,protein structure, tertiary
Faculty \ School: Faculty of Science > School of Biological Sciences
Depositing User: Pure Connector
Date Deposited: 09 Jul 2014 12:24
Last Modified: 16 Sep 2019 08:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/48893
DOI: 10.1105/tpc.104.026765

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