Early molecular events in PAMP-triggered immunity

Zipfel, Cyril (2009) Early molecular events in PAMP-triggered immunity. Current Opinion in Plant Biology, 12 (4). pp. 414-20. ISSN 1879-0356

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In plant innate immunity, the first line of microbial recognition leading to active defence responses relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs). This recognition leads to PAMP-triggered immunity (PTI). Despite the numerous PAMPs recognised by plants, only a handful of PRRs are characterised. For most, they correspond to transmembrane proteins with a ligand-binding ectodomain. PRRs interact with additional transmembrane proteins that act as signalling adapters or amplifiers to achieve full functionality. The crucial role of PRRs in anti-microbial immunity is demonstrated by the direct targeting of PRRs and their associated proteins by pathogenic virulence effectors.

Item Type: Article
Uncontrolled Keywords: host-pathogen interactions,immunity, innate,membrane proteins,models, biological,plant diseases,plant proteins,plants,protein binding,receptors, pattern recognition,signal transduction
Faculty \ School: Faculty of Science > School of Biological Sciences
UEA Research Groups: Faculty of Science > Research Groups > Plant Sciences
Depositing User: Pure Connector
Date Deposited: 09 Jul 2014 12:14
Last Modified: 24 Oct 2022 06:25
URI: https://ueaeprints.uea.ac.uk/id/eprint/48883
DOI: 10.1016/j.pbi.2009.06.003

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